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FTH1 inhibits ferroptosis through ferritinophagy in the 6-OHDA model of Parkinsons disease
Graphical Abstract 1 Introduction Cyclophosphamide (CY) is a commonly used chemotherapeutic alkylating agent for the treatment of breast cancer, non-Hodgkins lymphoma, multiple myeloma, sarcoma, and leukemia ( The pulmonary toxicity caused by CY was clinically well documented, dose-related, and manifested as either early-onset interstitial pneumonitis that presents as cough, hyperthermia, and dyspnea or late-onset pulmonary fibrosis with pleural thickening and non-productive cough that progresses to severe pulmonary insufficiency ( -SMA gene ( - SMA-expressing myofibroblasts accumulate and produce collagen and extracellular matrix proteins in alveolar structures
Health Benefits: Detoxification: Helps eliminate toxins and supports liver health
10.1016/j.bbr.2012.11.043 332
Nebenwirkungen sind dosisabhngig und klingen nach Anpassung der Anwendung meist schnell ab
When treating it with vitamin B12, its key to know if its caused by a lack of folate or B12
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