The mechanistically correct prediction is that GLP-1s should look worse than dieting on DXA-measured lean mass precisely because they improve the metabolic conditions that inflate the lean compartment
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Although damage to this core is usually irreversible, with protection from Hi1a, permanent brain damage could be preventable
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doi: 10.1001/jamapsychiatry.2024.4789 l Clinical observation and some preliminary studies suggest the GLP-1 medication semaglutidebetter known by brand names like Ozempic, Mounjaro, and Wegovycan reduce cravings and help individuals with alcohol use disorder reduce or stop drinking
