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Topical application of mizoribine suppresses CD4+ T-cell-mediated pathogenesis in murine dry eye

This is called the background risk

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The proportion of TPA-stimulated ROS-forming PMN ( Figure 5F ) fluctuated nonspecifically over time until 9 h pi and dropped rapidly to a nadir at 12 h pi , when only 88% of PMN could be stimulated, before maintaining the baseline level until the end of the trial