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In laboratory and preclinical studies, GHK-Cu has been reported to stimulate collagen synthesis in dermal fibroblasts, support production of glycosaminoglycans and elastin, and accelerate epithelialization in wound models

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Tsao CW, Lin YS, Chen CC, Bai CH, Wu SR

The pulsatile nature of this release is clinically significant: it mimics endogenous GH secretion rhythms, preserving downstream IGF-1 production, protein synthesis, and fat oxidation without the sustained GH elevation that can impair insulin sensitivity

Bang P, Stangenberg M, Westgren M, Rosenfeld RG

11 13 A report from Carney 11 noted that about 50% of MMNST cases are associated with the CNC, and, thus, it is also imperative to also screen patients for other manifestations of the CNC, especially in younger patients