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for instance, DT-109 (Gly-Gly-Leu) markedly reduced atherosclerosis and vascular calcification in nonhuman primates, underscoring the translational potential of tripeptide-based therapeutics for cardiovascular diseases [181]

10.1136/gut.2009.202515 145 GeorgescuD.AncusaO.GeorgescuL.IonitaI.ReiszD

BBB permeability is a major factor determining the cause, progression, outcome, and therapeutic effectiveness of different neurological impairments in postnatal life

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Additionally, targeted therapies such as BRAF inhibitors (e.g., Vemurafenib) for patients with B-RAF mutations and CTLA-4 antibody ipilimumab provide new therapeutic possibilities alongside conventional chemotherapy (241)