Common symptoms of SFN include: Burning pain, typically beginning in the feet and sometimes spreading to the hands Sharp, shooting, or electric-like pain Numbness and tingling Allodynia (pain from normally non-painful stimuli, like light touch) Hyperalgesia (increased sensitivity to pain) Autonomic symptoms such as abnormal sweating, blood pressure fluctuations, digestive issues, and bladder dysfunction Skin changes in affected areas SFN can be particularly challenging to diagnose because standard nerve conduction studies, which are commonly used to evaluate peripheral neuropathies, primarily assess large fiber function and often miss small fiber damage
NAD+, in simple words, performs the function of energy carriers, from the mitochondria to the mitochondrial enzymes, in turn supplying fuel to all cells
Others notice increased sleep disturbances , though the direction varies, with some sleeping better and others worse
Psychiatry 73 , 2431 (2013)
Hormone imbalance: Hormones affect your energy levels, mood, libido, and ability to lose weight
Patients with a history of thyroid cancer, thyroid nodules, or medullary thyroid carcinoma (MTC) in the family should disclose this to their PlexusDx clinician before starting tirzepatide, as GLP-1 agonists carry a theoretical risk signal for C-cell proliferation in animal models
