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Semaglutide vs endoscopic sleeve gastroplasty for weight loss

Would I advise anybody to inject a substance that has to be stored after the sterile integrity has been broken and which no longer comes from a guaranteed sterile source - no

Symptoms of deficiency, including fatigue, numbness, cognitive fog, and mood changes, may return over weeks to months

No human clinical data exists to confirm these timelines

In the STEP 1 trial, once-weekly 2.4mg semaglutide produced a mean 14.9% body-weight reduction over 68 weeks establishing GLP-1 agonism as a leading anti-obesity mechanism