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But the alternative chemical synthesis is not easy at scale

Within the folate cycle 5,10-methylene-THF is converted to 5-methyl-THF by methylene THF reductase which is encoded by the MTHFR gene

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10.1016/j.smallrumres.2006.12.001 Summary Keywords SeNPs, GSH, oxidative stress, bull, semen cryopreservation Citation Li S, Ren J, Zhang W, Wang B, Ma Y, Su L, Dai Y and Liu G (2023) Glutathione and selenium nanoparticles have a synergistic protective effect during cryopreservation of bull semen

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