Results Study population A summary of the study population without children with metabolic syndrome is presented in Table 1
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For individuals using Ozempic primarily for weight management, stopping abruptly may result in weight regain , as the appetite-suppressing effects will cease
In the subsequent Examination of Cardiovascular Outcomes with Alogliptin versus Standard of Care (EXAMINE) study of alogliptin there was no statistically significant difference in HF hospitalisation (3.9% vs 3.3% with placebo) [59], and in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS), the rate of hospitalisation for HF was 3.1% in both sitagliptin- and placebo-treated patients [60]
We did not find a significant linear relationship between dose (g/day) (coefficients = 0.09, p = 0.652) and duration (weeks) of intervention (coefficients = 2.68, p = 0.433) and changes in HOMA-IR (Figures 6D, 7D)