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(2020) 370:eabd4570

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The approval for Chronic Inflammatory Demyelinating Polyneuropathy (CDIP), announced Monday, was backed by data from the ADVANCE-CIDP 2 clinical trial, where treatment with GAMMAGARD LIQUID yielded a 94.4% responder rate, indicating a significant improvement in functional disability

Moreover, most clinical cancer therapies, including conventional chemotherapies 8 , radiotherapy 9 , or recent immune therapies 10,11 , have also been reported to undermine female fertility in various ways, which further distracts researchers attention on NRTP-induced ovarian damage

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GPs can prescribe B12 injections following appropriate investigation, which should include: Full blood count to identify macrocytic anaemia Serum B12 and folate levels to confirm deficiency (using laboratory-specific reference ranges) Methylmalonic acid and/or homocysteine when B12 results are borderline Intrinsic factor antibodies if pernicious anaemia is suspected Additional tests depending on clinical presentation (e.g., thyroid function, coeliac serology) When both B12 and folate deficiency are present, B12 should be replaced before folate to avoid precipitating subacute combined degeneration of the spinal cord