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PMID: 17220370 Fernandez-Checa JC, Kaplowitz N

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A trial on 13 psoriasis patients (10 of whom completed the trial) showed that fumaric acid ester treatment for 24 weeks led to significant improvements is psoriasis severity in 80% of participants

Additional experiments including a footshock-only control group demonstrated that while footshock alone induced normal fear extinction, PTSD-like mice showed significantly impaired extinction retrieval (Supplementary Fig

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The combination allows researchers to participate more fully in physical therapy programs