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For nausea and vomiting, dietary adjustments may include smaller, more frequent meals and avoidance of high-fat or spicy foods, which can exacerbate symptoms [34,35]

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These studies also point to complete resection being the mainstay of initial treatment, and, despite clear consensus expressed in the literature, the authors of both studies likewise advocated for the use of adjuvant radiation therapy and potentially chemotherapy due to the aggressive potential of MMNST

Inhibitors of the MDM2/p53 interaction, such as UBX0101 and RG7112 (RO5045337), and inhibition of the de-ubiquitinating ubiquitin-specific peptidase 7 (USP7) increase and stabilize p53 levels and have been investigated for their senolytic effects