Its not clear whether the same effect occurs in humans, and large reviews of human data from 2024 to 2025 have not shown an increased risk, but the family-history exclusion remains in place across all GLP-1 SmPCs
Other serious but rare side effects include pancreatitis, gallbladder problems, low blood sugar, kidney problems, allergies, increased heart rate, and depression or thoughts of suicide
They function as a team
& Kligman, A
Weight reduction has many positive effects, from improving insulin sensitivity to reducing the risk of cardiovascular diseases (40, 56, 57)
Immediate discontinuation is necessary in cases of suspected pancreatitis, severe hypersensitivity reactions (anaphylaxis or angioedema), pregnancy, or suspected medullary thyroid carcinoma