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The compound was developed by Peter de Keizer and colleagues at Erasmus University Medical Center (Rotterdam) and published in a landmark 2017 Cell paper (Baar et al., Cell 169:132-147) demonstrating selective induction of apoptosis in cellular senescence research models

Then, 20 L of Luciferin Detection Reagent was added per well and incubated for 30 min

At low doses , it is neuroprotective

Nitric oxide is a critical signaling molecule involved in vasodilation, blood flow regulation, immune function, and tissue repair

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It is well tolerated, easy for patients to self-administer, and it keeps mitochondrial support steady through the period when the body is doing the most cellular work