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Kumar P, Liu C, Hsu JW, Chacko S, Minard C, Jahoor F, Sekhar RV

The existing data highlights the need for continued research to further clarify receptor specificity, downstream signaling dynamics, and the broader biological implications associated with melanocortin system modulation

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All individuals were provided lifestyle counseling and randomized (flip of a coin) to receive either Wegovy or a matching placebo (a substance that has no therapeutic effect) for a total of 68 weeks

In NDDs signal strength is moderate and long