Department of Health and Human Services Food and Drug Administration (FDA)
8 , e2300211 (2024)
The surgery itself can have risks, including possible damage to the parathyroid gland (that can impact a patients ongoing calcium levels) or damage to the laryngeal nerve (which can impact swallowing and impair speech)
Those target genes include heme oxygenase 1 (HMOX-1), the main regulator of iron and heme metabolism (Suzen et al., 2022), NAD(P)H quinone dehydrogenase 1 (NQO-1), a reducer of ROS (quinones) (Ross and Siegel, 2021), and peroxiredoxin (PRX), which reduces peroxides (Chowdhury et al., 2009), among many others
(2018) 7:F1000 Faculty Rev-689
Glutathione synthesis: new insights into its neurological regulation