Taken together, ceramide-mediated PS exposure and cell shrinkage are one of the best-documented signaling pathways leading to erythrocyte death and efferocytosis of eryptotic cells
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Abbreviations ACP1 - acid phosphatase CAT - catalase FMN - flavin mononucleotide GPX - glutathione peroxidase GSH - plasma reduced glutathione GSSG - oxidised glutathione MHR - methemoglobin reductase SOD - Zn/Cu superoxide dismutase TMR - transmembrane reductase of ferricyanide Methemoglobin reductase (MHR) is an erythrocyte cytosolic system responsible for reactivating haemoglobin's ability to transport oxygen after it has been converted into methemoglobin by reactive oxygen species (Board & Pidcock, 1981
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In the field of protein science alone, this popularity is reflected in almost 36,500 papers on infrared spectroscopy of proteins published between 1949 and 2025