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Isolation of lysosome-enriched fractions HT-1080 cells were treated with Fento-1 (10 M) for 1 h, and lysosome-enriched fractions were isolated using a Lysosome Isolation kit (Abcam, ab234047) according to the manufacturers protocol

This combination strengthens the overall antioxidant defense system and supports immune function, detoxification, and cellular protection

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Lentz SR, Erger RA, Dayal S, Maeda N, Malinow MR, Heistad DD, and Faraci FM (2000)

In particular, in the context of sepsis, these mechanisms contribute to exacerbated vascular leakage, which further compounds vascular dysfunction and injury in ICU patients (Zhang et al., 2023)

Scientific Reports