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62 This presents the opportunity for the development of oral, topical, and injectable formulations, allowing for both whole-body NAD+-restoring benefits alongside more targeted administration, resulting in the ultimate inside-outside approach to aging (Table 2)

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One of its most common hereditary forms, spinocerebellar ataxia type 3 (SCA3), stems from a genetic mutation in the ATXN3 gene and progressively damages the cerebellum