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Repair-cell migration and anti-scarring

European Journal of Endocrinology, 1998

Figure 1: Chemical structure of Glutathione [source: Accessed: 10 Oct 2012] The presence of the reactive sulphydryl group (originating from the cysteine residue) gives rise to GSHs nucleophilic nature and so it reacts readily with electrophiles which can present high risk of toxicity to the cell by causing oxidative damage such as lipid peroxidation to cell membranes, and interfering with the activity of essential proteins and DNA synthesis

selective NNMT inhibitors such as 5-Amino-1MQ are prominent tool compounds for target validation [2,8,9]

Taking them both at night is also a great strategy for maximizing overnight tissue repair

Statements Author contributions SA: Conceptualization, Supervision, Visualization, Writing original draft, Writing review & editing