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Triple Agonists Adding glucagon agonism to GLP-1/GIP agonism creates triple agonists currently in clinical trials

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Collectively, these data support semaglutide-mediated weight loss as a key treatment strategy in patients with the obesity phenotype of HFpEF

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Materials and Methods Animals and Drugs Eight-week-old male BKS-Lepr em2Cd479 /Gpt (db/db) mice and C57BL/6N mice were purchased from Beijing Vital River Laboratory Animal Technology Co., Ltd (Beijing, China)