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Children with Down syndrome have abnormal metabolic profiles and show increased incidence of a large number of serious diseases including leukemia and diabetes [61]

It is part of a class of drugs called DPP4 inhibitors and works alongside a healthy diet and regular exercise to improve how your body manages blood glucose (sugar)

Daily use is common in research protocols, typically for 4-8 week cycles

Ponte Press, Bochum 2003, ISBN 3-920328-45-0, S

Formulation and delivery remain challenges

By identifying genetic predispositions before starting treatment, patients avoid months of trial-and-error dosing and medication switching