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OMIM 602858), the final enzyme in the synthesis of cholesterol, and as a result exhibit abnormally high serum concentrations of 7-dehydrocholesterol and its isomer 8-dehydrocholesterol (67)

Additionally, balance training (particularly for older adults to prevent falls) and flexibility exercises are advised (Table 3)

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These advances also align with the emerging paradigm of precision medicine in obesity, in which genetic predictors of response and adverse effects to GLP-1-based therapies may enable more individualized treatment strategies [24]