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To determine whether GLP-1 produced in pancreatic islets is a target for DPP-4 inhibitors, Gcg was reactivated in alpha cells of Gcg RA Null mice by crossing Gcg- null mice to PDX1Cre mice to generate Gcg RA PDX1Cre mice

Therefore, the protective effect of l-Carnitine on mitochondria was further evaluated using the Seahorse XF Cell Mito Stress test

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