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Recognizing this potential, the FDA approved a higher-dose formulation under the brand name Wegovy specifically for chronic weight management, indicated for clients meeting certain Body Mass Index (BMI) criteria

Medicare coverage expanded in 2023, but coverage remains plan-specific and often requires documented metabolic conditions or failed weight loss attempts

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Exenatide attenuates obesity-induced mitochondrial dysfunction by activating SIRT1 in renal tubular cells

Some studies reported improvements in testosterone levels, sperm quality and reproductive hormone markers among men with obesity

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