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Immune and Antioxidant Effects in Human Studies a randomized, placebo-controlled study (8 weeks, healthy adults, 5 g/day Chlorella) showed an increase in NK cell activity and changes in selected cytokines (IFN-, IL-1, IL-12) compared to placebo

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Research Insights 1

The postoperative care included administering buprenorphine (0.05 mg/kg subcutaneously) every 12 h for 48 h for pain management

--- The Dosing Protocol The study used a locally administered protocol, injecting near the joint rather than systemic subcutaneous injection

Figure 2 In summary, given the major influence of the gut and its microbiota on the overall immune/inflammatory system and on neuroinflammation, and considering the importance of the MGB axis, one can foresee that well designed diets, complements or treatments aiming at reducing dysbiosis and gut inflammation may have a beneficial effect on different PAIS