Our finding of similar incidence of non-fatal cardiovascular outcomes with GLP1-RA compared to DPP4i is in line with the recently published FLOW study that randomized people with early to mid-stage CKD to semaglutide or placebo, which reported similar incidence of non-fatal myocardial infarction and non-fatal stroke across the semaglutide and placebo treated groups, despite a significantly reduced risk of major kidney disease events and all-cause death 44
I was too sheepish to have a conversation with them about it, so I left the pen in my toiletry bag and didnt throw it in the trash until I got home
Market Segmentation: Semaglutide holds 58% share, liraglutide accounts for 42%, hospital applications dominate 63% usage, drug stores contribute 37%
But the shortages meant that it was legal for compounders to produce their own GLP-1 dupeswhich they did, at an unprecedented volume
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Constipation was reported in 24.2% of people taking semaglutide, compared to 11.1% taking the placebo