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The observed progressive increase in nephrotoxicity and hepatoxicity indices in carnitine-depleted rats was aligned with the progressive decrease in serum carnitine, which may justify the possible consideration of carnitine deficiency as a risk factor in MTX-mediated acute nephrotoxicity and hepatotoxicity

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Methods : Twenty-one (21) female adult albino rats were acclimatized for 10 days and then classified into three treatment groups, each containing seven rats

Metsera was a biotech firm developing subcutaneous GLP-1s with a structural modification that allows them to activate the GLP-1R without detaching from albumina blood protein responsible for molecule transport and preventing degradation

Med 390 , 497509 (2024)