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David Kellner, MD: I'm really glad you asked this question, because people with rheumatoid arthritis have an increased risk of cardiovascular disease, and it's actually the leading cause of death in RA patients

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At the time Calibrate was founded, there was little existing science on when, or whether, patients could keep the weight off after they stopped using GLP-1sbut the preponderance of research that has emerged since then suggests that few can maintain their weight loss once they stop using the drugs

Meanwhile, other studies demonstrate a reduction in compulsive behaviors like drinking and gambling