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Ahrn B, Masmiquel L, Kumar H et al (2017) Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2): a 56-week, double-blind, phase 3a, randomised trial

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Stress activates the hypothalamic-pituitary-adrenal (HPA) axis, culminating in cortisol release

The serum antioxidant ability is remarkably enhanced after APP treatment, which is closely related to the up-regulated serum GSH level, GSH/GSSG ratio and antioxidant enzyme activities after APP treatment