tirzepatide gip/glp-1 Beyond glycemia: Comparing to GLP-1 analogues Tirzepatide (GLP-1 / GIP)

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For the long-term MIA model, 49 animals were divided into four groups: saline/vehicle (n = 9 mice), MIA/vehicle groups (n = 10), MIA/liraglutide (n = 10), or dexamethasone (n = 10)

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447 It was found that higher level of NAMPT in serum in women is correlated with a much lower hepatic de novo lipogenesis (DNL) index, although they do not correlate with the DNL index, but had a correlation with a higher hepatic fat in men, implying a sex-dependent interpretation role of serum NAMPT level for NAFLD prognosis