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This review examines cancer-specific fungal communities, the impact of fungal microbiome on cancer cell progression, similarities between fungal differentiation and cells turning cancerous at biochemical and molecular levels, including the overlaps in signal transduction pathways between fungi and cancer

Hence, pathways and mechanisms need to be investigated for possible pharmacological intervention

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10.2307/3578091 [DOI] [PubMed] [Google Scholar] 54.Dethlefsen LA, Lehman CM, Biaglow JE, Peck VM

Endoplasmic reticulum stress-activated transcription factor ATF6 requires the disulfide isomerase PDIA5 to modulate chemoresistance

Another possibility suggests that the pituitary gland, when signaled to release more thyroid-stimulating hormone (TSH) fails to do so