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We also used the rd10/Serpinf1 -/- mouse model, in which the deficiency of Serpinf1 (the gene encoding pigment epithelium-derived factor (PEDF) protein) increases susceptibility to retinal degeneration 16

DOI: Published online: December 12, 2013 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

The higher 3.0 mg and 4.5 mg doses that were approved in 2020 demonstrated hemoglobin A1c reductions closer to 1.5% and slightly more weight loss

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