In endothelial cell models, BPC-157 significantly enhanced ERK1/2 phosphorylation in a dose-dependent manner, leading to increased cellular proliferation, migration, and vascular tube formation mediated through downstream activation of transcription factors c-Fos, c-Jun, and EGR-1
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Nonsignificant interactions were retained in the model and marginal main effects tested at the mean of other variables, to give the overall effect of anticoagulant and time to deproteinization controlling for all other variables
When reconstituted with 4.0mL of bacteriostatic water, the total concentration is 20mg/mL (80mg divided by 4mL)