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Currently, based on evidence from neuroimaging, postmortem studies, and cerebrospinal fluid testing, BBB dysfunction has been recognized as an early biomarker of neurodegenerative diseases (Yuan, et al
In ageing septic rats, ghrelin/growth hormone treatment reverses immunosuppression by inhibiting the production of TGF- through the vagus nerve (Zhou et al
Mai Z, Lin Y, Lin P, Zhao X, Cui L
A randomized, placebo-controlled trial published in Diabetes, Obesity and Metabolism found that semaglutide led to a 24% reduction in total daily energy intake compared to placebo, driven primarily by reduced appetite and fewer food cravings rather than nausea or food aversion