An older adult with poor appetite, anemia, and low B12 will often regain weight once the deficiency is corrected
Individuals taking metformin alongside Mounjaro face increased risk of B12 deficiency, as metformin is known to impair B12 absorption, and may require more frequent monitoring
Importantly, the current evidence gap should not be interpreted as evidence of ineffectiveness
Injectable pyridoxine is usually administered IM or IV, though some formularies include SubQ as a possible route
Rough handling during reconstitution can denature the molecule, breaking the bonds that make it biologically active
In a phase 1 trial, a PYY analogue (Y14 peptide) administered subcutaneously at 7- to 14-days intervals was safe and potentially efficacious (WL between 2.9 and 3.6 kg at 31 days, with a 3855% reduction in food intake vs