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Pyridone-conjugated monobactam antibiotics with gram-negative activity

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Because inhomogeneous cellular distribution of reacted and unreacted probes may bias the ratiometric calculations, especially at the subcellular resolution, we opted for RT instead of RT-NH 2 to achieve high-quality quantitative results in living cells

Some IgG subtypes form immune complexes with oxLDL that stimulate an inflammatory macrophage response and thereby worsen plaque development, while others may be atheroprotective 3,126,133 (Fig