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As a member of the leukocyte surface antigen family, DPP-4 plays an important role in the immune system, and can regulate inflammation, oxidative stress, cell adhesion, and apoptosis

Recent patents on endocrine, metabolic & immune drug discovery

Possible relation to pancreatitis or pancreatic adenocarcinoma Another type of study of the exocrine pancreas has been to give GLP-1 mimetics or DPP-4 inhibitors to animals over a prolonged period of time and evaluate the pancreas for evidence of pancreatitis or precancerous lesions

The clinical characteristics, prognostic factors, and treatment outcomes of sporadic MPNST (sMPNST) and NF-1 associated MPNST (NF-MPNST) cases were compared

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