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The combination leads to endothelial dysfunction, cholesterol deposition, inflammation, and finally, calcification.[ref] Oxidized phospholipids are primarily polyunsaturated fatty acids that are oxidized due to ROS, infections, or apoptosis
doi: 10.1371/journal.pone.0036095
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Hypoglycemia When used as monotherapy or with medications that do not cause hypoglycemia, semaglutide carries very low risk of low blood sugar because its insulin-stimulating effects are glucose-dependent
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Mitochondrial Energy Production L-Carnitine plays a critical role in transporting long-chain fatty acids into the mitochondrial matrix for -oxidation, supporting ATP generation and metabolic efficiency [Rebouche 2004]
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