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Contacts: Jeannie Padowski, WSU College of Pharmacy and Elson S

When weight loss occurs quickly, facial fat that provides structure and volume diminishes faster than skin can adapt, [4] resulting in: A hollowed appearance, particularly in the cheeks Changes in lip , cheek, and chin dimensions Increased visibility of facial wrinkles An overall aged appearance Interestingly, recent research suggests GLP-1 agonists might affect adipose (fat) tissue dynamics in ways that could contribute to accelerated ageing beyond just weight loss

Constipation typically appears in the first 48 weeks and improves within 12 weeks as your body adapts

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As such, they confer multiple health benefits, including anti-cancer properties and improved mental and gut health

[DOI] [PMC free article] [PubMed] [Google Scholar] [113].Zhang J, Chen C, Fu H