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However, the mainly difference is that the hydrophobic and hydrogen-bonding interactions contributed by the active site residues, H244, E256 and F264 in mushroom tyrosinase are not observed in the corresponding active site residues, P505, S515 and I523 of human tyrosinase (Supplementary Fig

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Cefalo CMA, Cinti F, Moffa S, Impronta F, Sorice GP, Mezza T, Pontecorvi A, Giaccari A

GMA105 is a fusion protein that combines GLP-1 fragments with a humanized monoclonal antibody against GLP-1R, while GMA106 includes an antagonistic GIPR antibody fused with GLP-1 molecules, achieving dual receptor activation