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Sharma A, Gerbarg PL, Brown RP

A study utilizing functional MRI found that administration of exenatide, a glucagon-like peptide-1 receptor agonist, decreased activation in areas such as the insula, amygdala, orbitofrontal cortex and putamen in response to food cues

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Aromatase converts testosterone to estradiol (estrogen), creating a vicious cycle where increasing belly fat leads to lower testosterone, which in turn promotes more fat storage

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[5] Calcium is vital for maintaining bone density during weight loss, when bone remodelling may be affected