10.1089/ars.2017.7237 5
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From pharmacokinetics to pharmacodynamics, factors like adiposity, inflammation, and insulin resistance influence drug efficacy, dosing, and safety across therapeutic areas
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The development of these agents underscores the continuous improvement of the pharmacokinetic and pharmacodynamic profiles of these peptide agents [ Table 1 ], expanding their applications beyond T2DM and obesity to encompass cardiovascular disease event reduction [ Table 2 ]