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Examination of the GCL from these different organisms suggests that the interplay between the redox-sensitive thiol-switch and dimerization of the plant enzymes occurred later in evolution and may be related to compartmentalization of glutathione synthesis in the chloroplast (Gromes et al., The sub-organellar localization of GCL raises questions about redox regulation of glutathione biosynthesis in plants

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The culture was usually grown in a liquid mineral salt medium (MSM) containing (L 1 ): 3.34 g K 2 HPO 4 , 0.87 g NaH 2 PO 4 , 2.0 g NH 4 Cl , 200 mg MgSO 4 .7H 2 O , 12 mg FeSO 4 .7H 2 O , 3 mg MnSO 4

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Some patients describe a quiet dulling of response not just to food but to everyday pleasures