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It can, depending on the medication and the dog's detoxification capacity

Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat

Rip3 targets pyruvate dehydrogenase complex to increase aerobic respiration in tnf-induced necroptosis

Trends Mol Med (2021) 27(9):895906

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[PubMed] [Google Scholar] 84.Ciappuccini R., Ansemant T., Maillefert J.-F., Tavernier C., Ornetti P