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For these reasons, people are taking to microdosing weight-loss drugs, or using less than the dose recommended by the manufacturer

Many patients observe changes occurring in a few weeks

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A development that has the potential to change this dynamic is the arrival of GLP-1 receptor agonist medications like semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro)

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By analyzing the patents and regulatory protections it appears that the earliest date for generic entry will be January 28, 2028