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selective NNMT inhibitors such as 5-Amino-1MQ are prominent tool compounds for target validation [2,8,9]

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Its dual GLP-1 and GIP receptor activation produced a 20.9% average body weight reduction at 72 weeks in the SURMOUNT-1 trial, and more recent SURMOUNT-5 head-to-head data confirmed its superiority over Semaglutide

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