Aging is no longer seen as a fate, but as a biological problem that can be broken down, understood and solved
Enhanced microcirculation is thought to facilitate delivery of metabolic substrates and signaling molecules necessary for connective tissue repair
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Cardoso JV, Machado DE, da Silva MC, Berardo PT, Ferrari R, Abro MS, Perini JA (2019) Matrix metalloproteinases 3 polymorphism increases the risk of developing advanced endometriosis and infertility: a case-control study
Second, the arginine at position 3 in the native sequence was substituted with leucine (hence R3)