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15-17 The first case report documenting the successful use of semaglutide in treating HS by Drumm et al 18 also showed a reduction in weight (24 kg), DLQI, narcotic analgesia use (from daily to not daily), and Hurley stage after six months of treatment

Experts say this is likely to be only the start of the use of this class of drugs in helping those with obesity lose weight

While they look identical in their powdered, vibrant blue state, their target affinities differ significantly

Studies have demonstrated GLP-1s can help people with obesity lose as much as 15% of their body weight, but research also shows that stopping the medication without sustained behavior changes puts people at risk for weight regain

Dr Restivo is a wealth of knowledge

Administration of GLP-1 and exendin-4 promoted neurite outgrowth in cultured dorsal root ganglion (DRG) neurons, presumably explaining the increased nerve fibers observed in biopsies of IBS individuals [51]