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TMT labeling of peptides Desalted peptides (250 g per sample) were labeled with TMT 18-plex reagents (500 g) in HEPES buffer, quenched with hydroxylamine and pooled across 13 plexes including a common reference channel

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The AKR1C3 inhibitor tolfenamic acid (Endo et al., 2011) and siRNA treatment increase the sensitivity of non-resistant PCa cells to docetaxel (DTX), suggesting a role of AKR1C3 in DTX resistance (Shen et al., 2011)

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But people are unaware that semaglutide, tirzepatide and retatrude (the weight loss drugs) are also peptides